If your mouse cursor is going the wrong way, the most common cause of this problem is the corrupted mouse driver. Update your mouse driver and then see if this fixes the problem. If there is no update available for your mouse driver, uninstall it and download the latest version from the manufacturer's website.
Why does my mouse go left when I go right?
Sometimes, the reason is simple, though not that obvious – your mouse could start scrolling in the wrong direction because of accumulated dust around the scrolling wheel. Old batteries are another common culprit causing wireless mice to scroll the wrong way. However, most often, the problem lies in the mouse driver.
How do I fix my mouse moving the opposite direction?
Press and hold down both mouse buttons. After 2, to 5 seconds the mouse pointer will position itself at the bottom of the screen and move upwards. Release the buttons and move the mouse pointer in a straight line upward until the pointer moves in a small circle. The new up direction will now be set.